Where to Go On a Malaria-free Family Safari in South Africa?

Published on 22 July 2012, Last updated on 12 March 2025.

By Landia Davies in Family Safari.

One of the few African countries to host many malaria-free game reserves, South Africa is an ideal African destination for a family safari with kids.

Unfortunately, most countries in southern and central Africa are considered high-risk malaria areas, but there are large parts of southern Africa that are malaria-free or at least low-risk malaria areas. Here are some malaria-free game parks in South Africa.

Malaria-Free South African Safaris for Families

Addo Elephant National Park in the Eastern Cape
Private Game Reserves in the Eastern Cape
Tsitsikamma National Park on the Garden Route
Other Garden Route Reserves & National Parks
Pilanesberg National Park (& Sun City) near Johannesburg
Madikwe Game Reserve in North West Province

Family Safaris to Malaria-Free Areas in South Africa:

Anti-malaria precautions are not necessary for South African safaris to Cape Town, the Garden Route, Durban, Johannesburg, Pilanesberg or destinations in any of the malaria-free provinces. Please note that if these South African tours to malaria-free areas also visit malaria-risk areas and game parks, then anti-malaria medication is recommended.

For help planning family safaris see How to Plan a Family Safari with Kids.

Malaria-Free Provinces in South Africa:

Western Cape
Eastern Cape
Free State
Gauteng

Although the North West and Northern Cape Provinces are also considered malaria-free, there are in fact some low-risk areas along the Molopo and Orange Rivers, near the Botswana and Namibia borders. These low-risk areas of the Kalahari Desert include Augrabies Falls and the Kgalagadi Transfrontier Park, where seasonal precautionary measures to prevent mosquito bites are recommended.

The Kingdom of Lesotho, a small landlocked country surrounded by South Africa, is also malaria-free. Although it is not a wildlife safari destination, Lesotho is a travel highlight with its pony trekking, beautiful mountain scenery and cultural richness.

Check out our Budget Lesotho Safaris.

Note: The Lesotho tours are only malaria-free if they do not also visit Kruger Park and Eswatini (or other malaria areas).

National Parks in Low-Risk Malaria Areas

Another option is to go on a wildlife safari in a low-risk malaria area, preferably during the low-risk seasons outlined further down.

Augrabies Falls and the Kgalagadi Transfrontier Park (Kalahari Gemsbok National Park section in South Africa) are low-risk areas. Malaria is only rarely transmitted in these Kalahari areas. To avoid being bitten by mosquitoes take the necessary precautions (see below).
Royal Natal National Park (Ukhahlamba Drakensberg National Park) is in the malaria-free Drakensberg Mountain Range, BUT the surrounding low-lying coastal areas are considered intermediate to low-risk malaria areas. Anti-malaria precautions are therefore recommended (take malaria prophylaxis).

Southern African Game Parks in Malaria Areas

It is advisable to take anti-malaria precautions in the following risk areas:

Kruger National Park & Greater Kruger Game Reserves (high-risk malaria area)
Hluhluwe-Umfolozi Park (intermediate to low-risk area)
Isimangaliso or Greater St. Lucia Wetland Park (intermediate to low-risk malaria area)
Mlilwane Nature Reserve in Eswatini (low risk in western Eswatini to high malaria risk in eastern areas)

All game parks in the Lowveld of Mpumalanga and Limpopo Provinces, and north-eastern KwaZulu-Natal (Maputaland coast) fall in malaria territory. Check with your doctor or local travel clinic to determine if anti-malaria medication is recommended, especially in the malaria season.

If you plan on going scuba diving in the northern part of KwaZulu Natal (or other malarial areas) then you will need to avoid certain anti-malaria medications, including Larium. Malaria prophylaxis containing mefloquine can cause negative side effects when combined with nitrogen. Be sure to consult your doctor to ensure that prophylaxis suitable for safe scuba diving is prescribed.

High and Low-Risk Malaria Seasons

Low-risk malaria season in South Africa:

From the end of May to early September during the cold dry winter months.

May through late August are considered the best months for game viewing in and around Kruger National Park as the malaria risk is lower and the bush is less dense.

High-risk malaria season in South Africa:

From late September / early October to May, in the wet summer months.

Throughout the year for high-risk people

Africa Map of Malaria Areas

Malaria Risk Countries in Africa

Other African countries all have a malaria risk, especially during the rainy seasons, even though the risk in some areas is very low.

Botswana -

From November to May-June in the northern parts of the country: Boteti, Chobe, Ngamiland, Okavango, and Tutume districts/ subdistricts.

Malawi -

The entire country throughout the year.

Mozambique -

The whole country throughout the year.

Namibia -

From November to June in the following regions: Ohangwena, Omaheke, Omusati, Oshana, Oshikoto and Otjozondjupa. Risk throughout the year exists along the Kunene River and in the Caprivi and Kavango regions.

Eswatini (Swaziland) -

Throughout the year in all low veld areas (mainly western parts).

Zambia -

Throughout the year in the whole country, including Lusaka.

Kenya -

Most of Kenya is a high-risk malaria area throughout the year, with some low-risk areas (including Nairobi and the highlands).

Tanzania -

The entire country is at high malaria risk throughout the year, except for areas above 1,800m in altitude.

Zimbabwe -

From November through June in areas below 1,200m and throughout the year in the Zambezi Valley. In Bulawayo and Harare, the risk is negligible.

Visit the WHO's Malaria Threat Maps to view global malaria distribution and get country-specific information about malaria risks.

People at High Risk of contracting malaria:

People at high risk who should take extra anti-malaria precautions are:

children under 5
adults over 65
pregnant women
people on long-term steroids
people receiving chemotherapy
people with Aids / HIV, porphyria or epilepsy
people who have had their spleens removed
chronically ill patients
immuno-compromised people

Anti-malaria precautions in low-risk areas and seasons include:

insect repellent creams (lotions) and sprays
mosquito netting (screens) over windows and doors
mosquito nets over beds or camping mattresses
light-coloured long sleeves, long pants and socks
staying indoors after dusk and before dawn
spraying insecticide in your accommodation (if necessary)

Signs of Malaria Infection

It is advised that you seek immediate medical attention if you have flu-like symptoms for up to six months after visiting a malaria area.

Flu-like symptoms are common symptoms of malaria. Including fever, rigours, headache, sweating, fatigue, myalgia (back and limb pain), abdominal pain, diarrhoea, appetite loss, a cough, and nausea and vomiting.
In young children, malaria symptoms include fever, lethargy, poor feeding and vomiting.

Important Facts about Malaria:

Malaria symptoms may only develop 10-14 days after being infected by a mosquito bite (if a person has taken chemoprophylaxis, this period can be even longer).
Be aware that the symptoms of malaria may be delayed and prophylaxis is not a 100% guarantee against malaria.
Insist on diagnostic tests if you develop a fever a week or more after visiting malaria areas.

Malaria Myths

"I wasn't bitten, so I can stop taking my prophylaxis"

The female anopheles mosquito is known as 'the silent killer' for good reason. This mosquito does not buzz loudly, so it may go unnoticed. The reaction to the mosquito bite may also be mild enough to go undetected.

"Prophylaxis need only be taken while in a malaria area"

It is extremely important to continue taking malaria prophylaxis for 4 weeks after leaving a malaria area. Consult your doctor.

To find out everything you need to know about malaria, see our blog post - Malaria Made Simple.

For more information about malaria-free family safaris in southern Africa or for information about malaria precautions and areas, contact African Budget Safaris.